Control of specific growth rate in Saccharomyces cerevisiae

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Control of specific growth rate in Saccharomyces cerevisiae.

In this contribution we resolve the long-standing dispute whether or not the Monod constant (K(S)), describing the overall affinity of an organism for its growth-limiting substrate, can be related to the affinity of the transporter for that substrate (K(M)). We show how this can be done via the control of the transporter on the specific growth rate; they are identical if the transport step has ...

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Calcineurin-dependent Growth Control in Saccharomyces cerevisiae

Ca 2÷ ATPases deplete the cytosol of Ca 2÷ ions and are crucial to cellular Ca 2÷ homeostasis. The PMC1 gene of Saccharomyces cerevisiae encodes a vacuole membrane protein that is 40% identical to the plasma membrane Ca :÷ ATPases (PMCAs) of mammalian cells. Mutants lacking PMC1 grow well in standard media, but sequester Ca 2÷ into the vacuole at 20% of the wild-type levels, pmcl null mutants f...

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ژورنال

عنوان ژورنال: Microbiology

سال: 2009

ISSN: 1350-0872,1465-2080

DOI: 10.1099/mic.0.023119-0